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Depression in cancer patients: a critical review

Massimo Pasquini1,2 email and Massimo Biondi1 email

1Department of Psychiatry and Psychological Medicine, University "La Sapienza" of Rome, Italy

2Dipartimento di Scienze Psichiatriche e Medicina Psicologica. Viale dell'Università 30 – Roma, 00185, Italia

author email corresponding author email

Clinical Practice and Epidemiology in Mental Health 2007, 3:2doi:10.1186/1745-0179-3-2

Published: 8 February 2007

Abstract

Cancer patients experience several stressors and emotional upheavals. Fear of death, interruption of life plans, changes in body image and self-esteem, changes in social role and lifestyle are all important issues to be faced. Moreover, Depressive Disorders may impact the course of the disease and compliance. The cost and prevalence, the impairment caused, and the diagnostic and therapeutic uncertainty surrounding depressive symptoms among cancer patients make these conditions a priority for research. In this article we discuss recent data, focusing on detection of Depressive Disorders, biological correlates, treatments and unmet needs of depressed cancer patients.


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