 Case reportObsessive compulsive disorder comorbidity in DBAStefano Pallanti1,2,3, Sara Masetti2, Silvia Bernardi2, Alice Innocenti2, Mariana Markella1 and Eric Hollander1 1
Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY, USA 2
Department of Psychiatry, Università degli Studi di Firenze, Florence, Italy 3
Istituto di Neuroscienze, Florence, Italy Clinical Practice and Epidemiology in Mental Health 2008,
4:6doi:10.1186/1745-0179-4-6 Abstract
Diamond-Blackfan Anemia (DBA) is a congenital erythroid aplasia characterized as a normochromic macrocytic anemia with a selective deficiency in red blood cell precursors in otherwise normocelullar bone marrow. DBA is known to be associated with mental retardation and learning disabilities. Although comorbidities with other psychiatric conditions have not been reported in the existing literature, we report in this paper a case of a DBA patient with previously undiagnosed comorbidity of obsessive compulsive disorder (OCD), successfully treated with sertaline 200 mg/day and valproic acid 600 mg/day. This case of comorbid presentation has clinical, therapeutic and pathophysiological implications. Given the difficulty of distinguishing among mental retardation, learning disabilities and OCD and the importance of precocious diagnosis in treating OCD especially since there are treatment methods interfering with anemia symptoms, physicians should adapt an adequate screening tool treating a child with DBA and comorbid mental disorder. | 
on Google Scholar
